15 interesting facts about antibiotics that will change attitudes to them
Antibiotics are a breakthrough in treatment.
Today, antibiotics are probably in everyone’s medicine Cabinet, and many people can’t imagine their lives without them, escaping with these drugs from a trivial cold, when it would be quite possible to do with tea with raspberry jam. This review contains little-known facts about antibiotics that will allow you to look at them from a different angle.
1. Barry MarshallTo prove that the cause of a stomach ulcer is bacteria, Barry Marshall drank a broth teeming with infectious bacteria, earned an ulcer, and then cured himself with antibiotics. He received the Nobel prize in 2005.
2. “Light of the angel”
During the American Civil war, the wounds of some soldiers… glowed. Curiously, soldiers whose wounds glowed had a better chance of survival, which is why the glow was called “angel Light”. It is now known that the luminescence was caused by bacteria that produce antibiotics and that live in nematodes.
3. Chronic diarrhea
The most effective method of treating pseudomembranous colitis (a bowel disease that causes chronic diarrhea) is fecal transplantation, during which the patient is injected with feces taken from a healthy donor (thus, healthy bacteria are transplanted into his digestive tract). This treatment is effective in 94%, compared to 30% for antibiotics.
4. Natural bacteria
Researchers have found natural bacteria in the human gut that inhibit the development of food allergies. The amount of these beneficial bacteria in the gut decreased when antibiotics were used frequently at a young age, which caused children to be more susceptible to food allergies later in life.
More than 30% of pharmaceuticals sold in developing countries are counterfeit. Approximately 50% of malaria medicines and up to 30% of antibiotics are counterfeit (produced mainly from India). Every year, more than 700,000 people die from the use of counterfeit medicines.
6. Moldy bread
Ancient Egyptians used moldy bread to treat infected burn wounds. Perhaps they were already using the antibiotic effects discovered by Alexander Fleming.
Before the advent of refrigerators, people threw frogs in milk to keep it fresh. The study of this phenomenon led to the discovery of new antibiotic substances.
8. The toxicity of penicillin
Early tests for penicillin toxicity were performed on live mice. If tests were carried out on other animals that are currently used (Guinea pigs), then there would simply be no antibiotics today. Penicillin is toxic to Guinea pigs.
9. Alexander Fleming
Alexander Fleming predicted an increase in antibiotic resistance. He did this in his speech at the awarding of the Nobel prize in 1945.
From the brain of cockroaches there are some serious antibiotics strong enough to kill the bacteria that have developed resistance to antibiotics. Moreover, they kill bacteria that are immune to drugs used to treat people.
In 2015, the first new antibiotic (Teixobactin) was discovered in about 30 years. This discovery could pave the way for a new generation of antibiotics. It was discovered using an electronic chip to grow microbes from the soil and then isolate their antibiotic chemical compounds.
In 1937, a pharmaceutical company began selling an antibiotic without prior testing. Because it was made using a known poison as a solvent, more than 100 people died as a result and the FDA (food and drug Administration) was formed.
Antibiotics are usually not effective for sore throats and colds, because they are caused by viruses, not bacteria. The use of antibiotics for such diseases is considered more harmful than useful.
It was discovered that ancient Nubian mummies had the modern antibiotic Tetracycline in their bones. The Egyptians got it from beer.
Due to the medicinal effects of thousands of pollen flowers and hydrogen peroxide, even MSRA and VRE bacteria have difficulty surviving.At the same time, honey retains all its properties.